faps (R&D Systems)
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R&D Systems
faps
Faps, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 79 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+fap/Human+PDGF+R+alpha+Antibody/pmc13082186-78-68-75
Average 93 stars, based on 79 article reviews
Faps, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 79 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+fap/Human+PDGF+R+alpha+Antibody/pmc13082186-78-68-75
Average 93 stars, based on 79 article reviews
faps - by Bioz Stars,
2026-09
93/100 stars
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Related Articles
Blocking Assay:Article Title: Injured Cardiac Tissue-Targeted Delivery of TGFβ1 siRNA by FAP Aptamer-Functionalized Extracellular Vesicles Promotes Cardiac Repair Article Snippet: Equal amounts of protein were separated by 10% sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and transferred onto polyvinylidene fluoride membranes (IPVH00010, EMD Millipore, Bedford, MA, USA). .. After blocking with 5% bovine serum albumin (BSA) in TBS-Tween 20 (TBS-T) for 1 h, the membranes were incubated with the following primary antibodies: anti-TSG101 (sc-7964, 1:1,000; Santa Cruz Biotechnology Inc., Dallas, TX, USA), anti-CD81 (sc-166029, 1:1,000; Santa Cruz Biotechnology Inc.), anti-GRP94 (sc-393402, 1:1000; Santa Cruz Biotechnology Inc.), Article Title: Fibroblast Activation Protein (FAP) + cancer-associated fibroblasts induce macrophage M2-like polarization via the Fibronectin 1-Integrin α5β1 axis in breast cancer. Article Snippet: Cancer-associated fibroblasts expressing fibroblast activation protein (FAP CAFs) are critical modulators of the breast cancer microenvironment, yet their immunoregulatory mechanisms remain poorly understood.. Through integrated analysis of single-cell RNA sequencing data, clinical specimens, and in vivo and in vitro experiments, we identified FAP CAFs as the predominant stromal population associated with poor clinical outcomes and immunosuppressive features.. Mechanistically, FAP CAFs secrete high levels of fibronectin 1 (FN1), which engages integrin α5β1 on macrophages to trigger FAK-AKT-STAT3 signaling, driving their polarization toward an immunosuppressive M2-like phenotype. Article Title: Injured Cardiac Tissue-Targeted Delivery of TGFβ1 siRNA by FAP Aptamer-Functionalized Extracellular Vesicles Promotes Cardiac Repair Article Snippet: Equal amounts of protein were separated by 10% sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and transferred onto polyvinylidene fluoride membranes (IPVH00010, EMD Millipore, Bedford, MA, USA). .. After blocking with 5% bovine serum albumin (BSA) in TBS-Tween 20 (TBS-T) for 1 h, the membranes were incubated with the following primary antibodies: anti-TSG101 (sc‐7964, 1:1,000; Santa Cruz Biotechnology Inc., Dallas, TX, USA), anti-CD81 (sc-166029, 1:1,000; Santa Cruz Biotechnology Inc.), anti-GRP94 (sc-393402, 1:1000; Santa Cruz Biotechnology Inc.), Incubation:Article Title: Injured Cardiac Tissue-Targeted Delivery of TGFβ1 siRNA by FAP Aptamer-Functionalized Extracellular Vesicles Promotes Cardiac Repair Article Snippet: Equal amounts of protein were separated by 10% sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and transferred onto polyvinylidene fluoride membranes (IPVH00010, EMD Millipore, Bedford, MA, USA). .. After blocking with 5% bovine serum albumin (BSA) in TBS-Tween 20 (TBS-T) for 1 h, the membranes were incubated with the following primary antibodies: anti-TSG101 (sc-7964, 1:1,000; Santa Cruz Biotechnology Inc., Dallas, TX, USA), anti-CD81 (sc-166029, 1:1,000; Santa Cruz Biotechnology Inc.), anti-GRP94 (sc-393402, 1:1000; Santa Cruz Biotechnology Inc.), Article Title: Fibroblast Activation Protein (FAP) + cancer-associated fibroblasts induce macrophage M2-like polarization via the Fibronectin 1-Integrin α5β1 axis in breast cancer. Article Snippet: Cancer-associated fibroblasts expressing fibroblast activation protein (FAP CAFs) are critical modulators of the breast cancer microenvironment, yet their immunoregulatory mechanisms remain poorly understood.. Through integrated analysis of single-cell RNA sequencing data, clinical specimens, and in vivo and in vitro experiments, we identified FAP CAFs as the predominant stromal population associated with poor clinical outcomes and immunosuppressive features.. Mechanistically, FAP CAFs secrete high levels of fibronectin 1 (FN1), which engages integrin α5β1 on macrophages to trigger FAK-AKT-STAT3 signaling, driving their polarization toward an immunosuppressive M2-like phenotype. Article Title: Injured Cardiac Tissue-Targeted Delivery of TGFβ1 siRNA by FAP Aptamer-Functionalized Extracellular Vesicles Promotes Cardiac Repair Article Snippet: Equal amounts of protein were separated by 10% sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and transferred onto polyvinylidene fluoride membranes (IPVH00010, EMD Millipore, Bedford, MA, USA). .. After blocking with 5% bovine serum albumin (BSA) in TBS-Tween 20 (TBS-T) for 1 h, the membranes were incubated with the following primary antibodies: anti-TSG101 (sc‐7964, 1:1,000; Santa Cruz Biotechnology Inc., Dallas, TX, USA), anti-CD81 (sc-166029, 1:1,000; Santa Cruz Biotechnology Inc.), anti-GRP94 (sc-393402, 1:1000; Santa Cruz Biotechnology Inc.), Article Title: CD206+ macrophages facilitate wound healing through interactions with Gpnmb hi fibroblasts Article Snippet: .. Next, slides were blocked for 1 h with 10% donkey serum prior to incubation with the following primary antibodies at 4 °C overnight: anti-CD206 (MCA2235GA, Bio-Rad, CA, USA; 1:200), anti-engrailed-1 (PA5-14149, Thermo Fisher Scientific, CA, USA; 1:200), anti-CD26 (AF954, R&D Systems, MN, USA; 1:200), other:Article Title: CTC-derived pancreatic cancer models serve as research tools and are suitable for precision medicine approaches Article Snippet: |